For laboratory research use only. Every lot independently tested; certificates published by lot.

Buying MOTS-c? Check the lot first.

Buy MOTS-c online: current lot, price and certificate

MOTS-c Research Supply is a buyer's guide to MOTS-c research material: sizes, prices, the current lot's independent results and how ordering through Klow.bio works. Current availability is provided through Klow.bio.

For laboratory research use only. MOTS-c Research Supply does not provide medical advice or usage guidance.

Certificate summary, lot KB-44745 MOTS-c 10 mg
Purity (HPLC-UV)
99.90%
Identity (HPLC-RTM)
Confirmed
Net content
10.71 mg
Reported
Sep 11, 2026
From the ILS Laboratories certificate COA-2026-WCUV5P. Open the full lot record.
99.90%
HPLC-UV purity, current lots
1 of 1
Lots with identity confirmed by HPLC retention-time match against a reference standard
Not detected
Fentanyl screen, current lots
100%
Lots tested by an independent lab
Full COA
Certificate PDF published for every lot

MOTS-c at a glance

The essential facts about MOTS-c and MOTS-c Research Supply. Every figure on this page comes from the published certificates of analysis or the product specification.

Product
MOTS-c
Type
16-residue mitochondrial-derived peptide, 16 residues
Also known as
Mitochondrial open reading frame of the 12S rRNA type-c
CAS number
1627580-64-6
Molecular formula
C101H152N28O22S2
Molecular weight
2174.62 g/mol (average)
Form
Lyophilized powder
Vial sizes
10 mg, 40 mg
Purity, current lots
99.90% (HPLC-UV)
Purity specification
≥95%
Identity
Confirmed by HPLC retention-time match on every lot
Testing laboratory
ILS Laboratories (independent)
Current lot
KB-44745, reported Sep 11, 2026
Operated by
Klow Labs LLC, Chicago, IL
Where to order
klow.bio

Last updated

MOTS-c research peptide

What is MOTS-c?

MOTS-c is a 16-residue peptide (2174.62 g/mol) with two methionines and a tryptophan, which is why storage and testing date both matter when you buy it. The current lot, KB-44745, was tested by ILS Laboratories: 99.90% HPLC purity, identity confirmed against a reference standard, 10.71 mg in a 10 mg vial, fentanyl screen negative.

MOTS-c is offered in 10 mg and 40 mg vials at $39.99 to $119.99 through Klow.bio. Sizes without a published lot are marked as such on this site rather than borrowing another size's certificate.

Structural features that matter for analysis

The sequence has two methionines (positions 1 and 6) and one tryptophan (position 3), the residues most prone to oxidation, so MOTS-c is best kept dry, sealed and away from light. Arg2, Arg13, Lys14 and Arg16 make it strongly basic. Two tyrosines and a phenylalanine add UV absorbance at 214 nm and 280 nm.

Sizes and ordering

MOTS-c is supplied as a lyophilized powder in 10 mg and 40 mg vials. It is sold through klow.bio, operated by Klow Labs LLC, where current pricing, bundle discounts and shipping options are listed. Orders ship the next business day. Same-day cutoff is 4:00 PM CT, with overnight and 2-day options at checkout.

MOTS-c specifications
ProductMOTS-c
Type16-residue mitochondrial-derived peptide
Molecular formulaC101H152N28O22S2
Molecular weight2174.62 g/mol (average)
Length16 residues
SequenceMRWQEMGYIFYPRKLR
N-terminusFree amine (Met1)
C-terminusFree acid (Arg16)
CAS number1627580-64-6
FormLyophilized powder
Vial sizes10 mg, 40 mg
Purity specification≥95% (HPLC-UV)
Purity, current lots99.90%
StorageStore sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening.
DesignationResearch use only

Where to buy MOTS-c for research

MOTS-c research material from MOTS-c Research Supply is available through klow.bio, the online store of MOTS-c Research Supply’s parent company, Klow Labs LLC. Product information, lot results and the certificate of analysis for every lot are published here on buymotscpeptide.com.

MOTS-c comes in 10 mg and 40 mg vials, currently priced from $39.99 to $119.99 depending on size, with bundle pricing (2 vials save 5%; 3 or more vials save 10%). Orders ship the next business day. Same-day cutoff is 4:00 PM CT, with overnight and 2-day options at checkout.

Vial sizeCurrent lotPurity (HPLC-UV)IdentityNet contentEndotoxinCertificateOrder
10 mg KB-44745 99.90% Confirmed 10.71 mg Not tested Lot KB-44745 Order 10 mg
40 mg Certificate pending Order 40 mg

What MOTS-c Research Supply documents for every MOTS-c lot

MOTS-c Research Supply publishes lot-specific analytical documentation for its MOTS-c research material. Each item below is published for every lot and can be checked against the laboratory record.

Independent testing

Every lot is tested by ILS Laboratories, an independent analytical laboratory. Published results come from the laboratory's certificate, not in-house testing.

The whole certificate, not a number

Every lot's certificate is published as a PDF, with the chromatogram behind the purity figure, alongside a readable lot record.

Identity confirmed on every lot

The laboratory runs the sample and a reference standard of the named compound under the same HPLC conditions; identity is confirmed when the main peak elutes at the reference standard’s retention time. The method is named on every lot record, so it is clear what the result does and does not establish.

Results against specification

Current lots test at 99.90% by HPLC-UV, well above the ≥95% release specification, with net content measured on every lot.

Verifiable at the source

Every certificate carries the laboratory's QR code. You can confirm results directly with the lab instead of taking our copy on trust.

Clear about limits

Lots without endotoxin or microbial testing say "Not tested". Each certificate page explains what the tests do and don't establish.

How to evaluate a MOTS-c supplier

The questions worth asking any supplier of MOTS-c research material, why each one matters, and how MOTS-c Research Supply answers them.

What to checkWhy it mattersMOTS-c Research Supply
Independent third-party testingResults produced by the seller can't be checked independently.✓ Every lot tested by ILS Laboratories
Lot-specific certificatesA generic certificate may not describe the vial you receive.✓ Each COA tied to the lot number on the vial label
Chromatogram availableA purity figure without the trace behind it can't be evaluated.✓ In the certificate PDF for every lot
Separate identity testHPLC purity shows how much of the sample is the main peak, not which compound the peak is.✓ HPLC retention-time match on every lot
Measured net contentConfirms how much peptide is actually in the vial.✓ Measured on every lot; current lots at or above label size
Contaminant screeningChecks for a specific contaminant the laboratory screens for.✓ Fentanyl screen on every current lot: not detected
Verifiable with the labPrevents altered or reused certificates.✓ Lab QR code on every certificate
Named company and contactAccountability requires a real business you can reach.✓ Klow Labs LLC, Chicago; (708) 262-7687

Current lots and certificates of analysis

Each row is one tested lot. Figures are copied from the laboratory certificate; open a lot to see its full record and download the certificate PDF.

LotVial sizeNet contentPurity (HPLC-UV) Identity (HPLC-RTM)Endotoxin (LAL)Microbial (PCR)ReportedCOA
KB-44745 10 mg 10.71 mg 99.90% Confirmed Not tested Not tested View lot KB-44745

Testing laboratory: ILS Laboratories. Release specification: purity ≥95% by HPLC-UV with identity confirmed by HPLC retention-time match against a reference standard. Results apply only to the lot listed. Certificates list the testing client as Klow.bio / Klow Labs LLC, the company that operates MOTS-c Research Supply.

Lot-to-lot consistency

The current lot tested at 99.90% by HPLC-UV. Lot-to-lot comparisons will appear here as further lots are tested.

Measured net content was at or above the labeled vial size for every current lot: 10.71 mg in a 10 mg vial.

HPLC-UV purity by lot. The scale runs from 99.0% to 100% so small differences are visible; every lot shown meets the ≥95% release specification.

How identity is confirmed

A purity figure says the sample is homogeneous; it does not say which compound the main peak is. That is answered by a separate identity test: HPLC retention-time comparison with a reference standard (HPLC-RTM).

The laboratory runs the sample and a reference standard of the named compound under the same HPLC conditions; identity is confirmed when the main peak elutes at the reference standard’s retention time. A retention-time match is consistent with the named compound under the laboratory’s method. It is not a mass measurement, which is why the method is always named next to the result.

How each test works and what it can’t show

Current MOTS-c lot
ProductMOTS-c 10 mg
LotKB-44745
Testing laboratoryILS Laboratories
Received / reportedSep 9, 2026 / Sep 11, 2026
Purity (HPLC-UV)99.90%
Identity (HPLC-RTM)Confirmed
Net content10.71 mg
FentanylNot detected
Endotoxin / PCRNot tested / Not tested
Certificate numberCOA-2026-WCUV5P
Lab access codeJDEMGBAM

Analytical testing on MOTS-c

Four methods appear on MOTS-c certificates. Each answers a different question, and none answers every question on its own, which is why they are used together.

HPLC-UV purity

Answers: how much of the sample is the main compound?

Reversed-phase high-performance liquid chromatography separates the sample's components by hydrophobicity, and a UV detector records each as a peak. Purity is the main peak's area as a percentage of all detected peak area.

Limits: does not identify the peak, and impurities that co-elute or absorb weakly in UV can be under-counted. More on HPLC

Identity by HPLC retention-time match

Answers: does the main peak behave like a MOTS-c reference standard?

The laboratory runs the sample and a reference standard of MOTS-c under the same chromatographic conditions. Identity is reported as confirmed when the sample’s main peak elutes at the reference standard’s retention time.

Limits: a retention-time match is consistent with the named compound but is not a mass or structure measurement; compounds with similar retention can co-elute. More on HPLC

Fentanyl screen

Answers: is the named contaminant present above the assay cutoff?

The laboratory screens each lot by immunoassay at the cutoff printed on the certificate. Current lots are reported as not detected.

Limits: a negative result means below the cutoff for the sample tested; an immunoassay screens for its target only.

Net content

Answers: how much MOTS-c is in the vial?

The laboratory quantifies the main compound in the tested vial against a standard. It is reported in milligrams next to the labeled vial size.

Limits: measured on the vial tested; other vials from the same lot are expected to be similar but are not individually measured.

From lot to published certificate

  1. Lot assignedA lot number is assigned and printed on every vial label.
  2. Sample sentVials from the lot go to ILS Laboratories, an independent lab.
  3. AnalysisHPLC-UV purity, HPLC-RTM identity and net content, plus endotoxin and PCR where listed.
  4. ReviewResults are compared with the stated specification: ≥95% purity, identity confirmed.
  5. PublishedThe lot record and certificate PDF are posted at /coa/ under its lot number.
  6. VerifiableAnyone can look the lot up at /verify/ and confirm it with the laboratory.

Full testing methodology

Verify your vial's certificate

You shouldn't have to take a supplier's word for its results. Here's how to check a MOTS-c certificate yourself.

  1. Find the lot number on your vial. It is printed on the label, for example KB-44745.
  2. Look it up. Enter it at buymotscpeptide.com/verify, or open the matching lot in the COA archive.
  3. Check the lab's own record. Go to portal.ils-lab.com (or scan the QR code on the certificate) and enter the lot's verification access code, listed on its lot page, to view the laboratory's own copy of the certificate.
  4. Compare the details. Lot number, the laboratory’s reference numbers, purity and dates should match exactly.

What a certificate of analysis does and doesn't show

  • A COA reports the identity, purity and content of the specific sample tested, on its test date. Results apply to that lot only.
  • HPLC purity measures the main peak relative to other detected components. It does not identify the peak on its own; the separate identity test (HPLC retention-time match) does that.
  • A retention-time match shows the main peak behaves like the reference standard under one method. It is not a mass or structure measurement.
  • Endotoxin and microbial results apply only where those tests appear on the certificate. Lots without them are marked "Not tested".
  • A certificate does not establish stability after the test date or suitability for any particular purpose.

Frequently asked questions about MOTS-c

What is MOTS-c?

MOTS-c is a 16-residue mitochondrial-derived peptide. MOTS-c Research Supply supplies it as a lyophilized powder in 10 mg, 40 mg vials, with an independent certificate of analysis for every lot.

What is MOTS-c research material?

MOTS-c research material is MOTS-c supplied for laboratory research, sold by lot, with each lot's identity, purity and net content documented by an independent laboratory in a published certificate of analysis.

What is the molecular formula and weight of MOTS-c?

The molecular formula is C101H152N28O22S2 and the average molecular weight is 2174.62 g/mol. The peptide has 16 residues.

How is MOTS-c analyzed?

MOTS-c is analyzed with complementary methods: HPLC-UV for purity, HPLC-RTM for identity, a quantitative measurement for net content, and, where listed, LAL endotoxin and PCR microbial testing. Results are published per lot at buymotscpeptide.com/coa/.

Who tests MOTS-c?

Every lot is tested by ILS Laboratories, an independent third-party analytical laboratory. MOTS-c Research Supply does not test its own material for published certificates.

What purity does MOTS-c test at?

Current lots report HPLC-UV purity 99.90%, against a stated release specification of ≥95%. The most recent result is 99.90% for lot KB-44745.

What is a MOTS-c COA?

A MOTS-c certificate of analysis is the testing laboratory's report for one lot: the lot number, test dates, methods and results for purity, identity and net content. MOTS-c Research Supply publishes every lot's COA as a readable page at buymotscpeptide.com/coa/.

Where can I find the COA for my vial?

Find the lot number printed on your vial label and enter it at buymotscpeptide.com/verify/, or open that lot in the COA archive at buymotscpeptide.com/coa/.

How do I confirm a COA with the laboratory?

Go to portal.ils-lab.com (or scan the QR code on the certificate) and enter the lot's verification access code, listed on its lot page, to view the laboratory's own copy of the certificate.

Where can I buy MOTS-c?

Current MOTS-c research material availability is provided through Klow.bio, the purchasing platform operated by Klow Labs: https://klow.bio/product/mots-c/ Lot records, testing information and certificates of analysis are published on buymotscpeptide.com so they can be reviewed before purchasing.

Can I order MOTS-c?

Yes. Purchasing information and current availability for MOTS-c research material are provided through Klow.bio: https://klow.bio/product/mots-c/

Is every MOTS-c lot independently tested?

Yes. Every lot is tested by ILS Laboratories, an independent laboratory, for HPLC-UV purity, HPLC-RTM identity and net content. The stated release specification is ≥95% HPLC-UV purity with identity confirmed by HPLC retention-time match against a reference standard. The current lot, KB-44745, reported 99.90% purity.

All questions and answers

About MOTS-c Research Supply

MOTS-c Research Supply is a buyer's guide to MOTS-c research material: sizes, prices, the current lot's independent results and how ordering through Klow.bio works.

MOTS-c Research Supply operates buymotscpeptide.com and supplies one research material, MOTS-c, with the analytical record behind every lot. MOTS-c Research Supply is operated by Klow Labs LLC, a Chicago company that also operates klow.bio, where MOTS-c is sold.

Our job is narrow on purpose: supply a well-characterized research material and publish the evidence for what is in each vial. We do not provide medical advice, protocols or usage guidance.

About MOTS-c Research Supply, research updates or Contact us

Legal entity
Klow Labs LLC
Address
3838 N Ravenswood Ave PMB 2027, Chicago, IL 60613
Contact
contact@klow.bio
(708) 262-7687
Testing laboratory
ILS Laboratories

Buy MOTS-c

10 mg and 40 mg vials. Current lot KB-44745 tested at 99.90% purity with identity confirmed by HPLC retention-time match against a reference standard. Current purchasing is available through Klow.bio.